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In “A Physician’s Guide to Coping with Death and Dying” Jan Swanson and Alan Cooper, a physician and a clinical psychologist with many years of experience, offer insights to help medical students, residents, physicians, nurses, and others become more aware of the different stages in the dying process and learn how to communicate more effectively with patients and their families. They also discuss the ways physicians and other caregivers can learn to reduce their own stress levels and avoid the risk of burnout, allowing them to achieve balance in their lives and be more effective professionally.
When Anni Matthews was diagnosed with cancer, she decided to do something really valuable with the experience: she produced a book that is a friendly companion for those who must face the disease.
Of huge practical help to anyone diagnosed with cancer and those who care for them, this book is a one-stop guide to making sense and use of the orthodox treatments, complementary therapies, and psychological, spiritual and holistic options available. Subjects ranging from the most current major advances in treatments and diagnosis to the small but effective ways of relieving the side-effects are explained clearly and concisely, often with humour and always with warmth.
Written by a bright, articulate woman, who was determined to have an informed say in what happened to her, Anni’s Cancer Companion marks a new generation of books about cancer. It is that rare thing: a reference book that is human.
BESTMEDICINE is a series of practical, authoritative and independent guides which provide patients, carers and the general public with information previously only available to the medical profession. BESTMEDICINE Hypertension discusses the importance of effective blood pressure control and the pivotal role that hypertension plays in the development of serious chronic diseases such as coronary heart disease. Detailed evidence underlying the use of one class of prescription medicines that are available to control blood pressure is also presented in this title, together with an overview of the other antihypertensive agents that are currently available.
This title offers comprehensive coverage of the best clinical management in primary care. It is based on the curriculum of Update (a primary care journal), in which topics are approached on a structured, modular basis. Each topic tackles a key therapy area in general practice over four issues of Update,including a practice-informed article written by a specialist. These modules have been edited into a full-colour book format, which will be published in 2 volumes, covering the entire curriculum. This book is the first of those volumes.
The Update curriculum on which the book is based is a PGEA approved Distance Learning programme, and as GPs are required to fulfill 24 PGEA hours each year, this title should prove an invaluable tool to help achieve this. Up to 10 PGEA hours are available using the self-assessment and multiple choice questions at the end of each volume, which GPs will be able to send to Update with a fee for certification.
There are a number of books about complementary therapies for nurses, but these mostly take a therapy-led approach. This new book, written by an experienced nurse, health visitor and teacher, uses a problem-based approach that relates to conditions presenting in everyday practice.
Childrens health, psychological and social needs are qualitatively and quantitatively different from those of adults and the author has for this reason addressed not only medical conditions but also psycho-social development problems.
Well-referenced and evidence-based, this book is an essential companion for all healthcare professionals who treat children and young adults.
Key Features
Decision making in health care involves navigating through a complex and tangled web of diagnostic and therapeutic uncertainties, patient preferences and values, and costs. Medical therapies have side effects, surgery may lead to undesirable complications, and diagnostic technologies may produce inconclusive results. In many clinical and health policy decisions it is necessary to counterbalance benefits and risks, and to trade off competing objectives such as maximizing life expectancy vs optimizing quality of life vs minimizing the resources required. This textbook plots a clear course through these complex and conflicting variables. It clearly explains and illustrates tools for integrating quantitative evidence-based data and subjective outcome values in making clinical and health policy decisions. The book will be of immense practical value for all those charged with the responsibility of decision making in medicine, including practitioners and trainees, and for students studying clinical decision analysis, EB-medicine, and clinical epidemiology.
This book introduces the fundamentals of dermal needling therapy, such as the principles of treatment, characteristics, indications, management of and precautions with accidents during treatment. It supplies the locations and the indications of commonly-used acupuncture points of the fourteen channels as well as extra points. It also outlines the principles for differentiating syndromes, treatment, point combination, and point selection, as well as presents the treatment for 86 common diseases in internal medicine, external trauma, orthopedics, gynecology, pediatrics, dermatology and otolaryngology. Each disease includes such parts as overview, cause and mechanism of disease, types of syndrome and treatment.
At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA! And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. How is this feat accomplished? What happens when errors occur? This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of targeted therapeutics is also addressed. At least 160 proteins are involved in replicating the human genome, and at least 40 diseases are caused by aberrant DNA replication, 35 by mutations in genes required for DNA replication or repair, 7 by mutations generated during mitochondrial DNA replication, and more than 40 by DNA viruses. Consequently, a growing number of therapeutic drugs are targeted to DNA replication proteins. This authoritative volume provides a rich source of information for researchers, physicians, and teachers, and will stimulate thinking about the relevance of DNA replication to human disease.
Evidence-Based Medicine Guidelines fills the demand for a handbook discussing the diagnosis and treatment of a wide range of diseases and conditions encountered by health care professionals.
The title was first published in Finland by the Finnish Medical Society, where it is now considered to be the single most important support tool for the physicians’ decision making in their daily work.
What sets EBM Guidelines apart from competing books?
Easy-to-read and fast support at the point of care – EBM Guidelines:
Based on the curriculum of the Royal College of Obstetricians and Gynaecologists’ Advanced Training Skills Module in Fetal Medicine, this book provides a comprehensive knowledge base for all doctors practising in obstetrics and maternal-fetal medicine worldwide. It acts as a reference source for the many changing concepts in fetal medicine and is well-illustrated with images of normal and abnormal findings in pregnancy that will facilitate proper understanding of normal and pathological fetal development. Coverage includes embryology, fetal physiology; fetal anomalies; fetal diseases; prescribing and teratogenesis in pregnancy; termination of pregnancy; fetal growth and wellbeing; multiple pregnancy; the placenta and amniotic fluid; and diagnostic and therapeutic invasive procedures. Readers will benefit from the theoretical knowledge and vast clinical experience of the internationally renowned authorship. Overall this book will prepare you for dealing with congenital abnormalities detected during pregnancy, including the organization and supervision of screening programmes for structural and chromosomal anomalies.
In this monograph about gene therapy of autoimmune and inflammatory d- orders we have gathered international experts and leaders from different fields to review the state of the art advances on topics ranging from disease entities to vectors and engineered cells. The different approaches described in each chapter take into consideration the biomedical knowledge of these diseases and address the complexities of delivering long-term genetic interventions. Gene therapy also serves as a testing ground for new therapeutic entities and helps provide proof of principle for their potential therapeutic role in animal models of disease. Scaling up from mice to men still remains an important h- dle not only from the quantitative point of view, but also for currently unknown and unexpected secondary effects of the vector or the transgene. Some of these approaches have already been tested in the clinic, but much more needs to be done to understand the human conditions treated and the n- ural history of their pathology. We are indebted to the secretarial assistance of Ms. Lin Wells (Bone and Joint Research Unit, London, UK) and the help of Hans Detlef Klüber for his help in getting this book published. We hope this book will be of interest to c- nicians and scientists and inspiring to students of the subject who will use their own ingenuity and knowledge to further forward this discipline into clinical use.
A practical, clinically-oriented handbook of iron overload disorders giving a compact guide to normal iron metabolism, iron-related pathobiology, and the diagnosis and management of heritable and acquired iron overload disorders. Many of these disorders were discovered and characterized only in the last decade, and are unmentioned or inadequately described in most texts. Written by clinicians for clinicians, this handbook summarizes information on diverse iron overload conditions, including their history, signs, symptoms, and physical examination findings, genetics, genotype-phenotype correlations, pathophysiology, differential diagnosis and treatment. Most physicians, regardless of specialty, encounter patients with systemic or organ-specific iron overload conditions. This book contains essential information for practising adult and pediatric medical specialists in the fields of hematology, gastroenterology, hepatology, rheumatology, endocrinology, diabetology, neurology, oncology, dermatology, and internal medicine. Pathologists, pharmacologists, geneticists, genetic counselors, and epidemiologists will also find substantial, up-to-date sections in this handbook that are pertinent to their respective fields of interest.
Adapting to the IFCC system of reporting HbA1c poses a challenge to generations of health professionals who have learnt the percentage system related to the major clinical trials, in type 1 and type 2 diabetes, the DCCT and UKPDS. This handy paperback illuminates the transition path.
Using real-life case studies to illustrate actual clinical situations, the book shows you how to use mmol/mol units in daily practice. Each case study shows the old percentage units alongside the IFCC units for quick comparison. Produced in association with Diabetes UK, this pocketbook helps you work with confidence in the IFCC system.
This definitive and comprehensive account of the human herpes viruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein Barr virus, cytomegalovirus and varicella-zoster virus. The diseases they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology if infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth and the volume is fully up to date both scientifically and in terms of clinical guidelines for patient care. The text is generously illustrated throughout and fully referenced to the latest research and developments.
Deficiencies and shortfalls in the supply of human organs for transplantation and human tissue for research generate policy dilemmas across the world and have often given rise to major and deleterious controversies, such as those relating to organ and tissue retention practices following post-mortem examination. They also create an environment in which illegitimate commercial activities flourish. At the same time, patients are denied the therapy they desperately require and researchers are impeded from carrying out vital work into the causes of, and efficacious treatments for, major illnesses and diseases. David Price sets out a clear and integrated legal and policy framework which emanates from the tissue source but protects the interests of donors and relevant professionals through tailored property entitlements, but without presupposing rights to trade in ‘original’ materials.
The third edition of this well-received text provides a state-of-the-art treatise on modern clinical practice relating to hyperlipidaemia and lipoprotein disorders, conditions responsible for a huge amount of morbidity and mortality in Western countries and, increasingly, the developing world. The clinical evidence underlying the treatment of hyperlipidaemia has burgeoned since the second edition published in 1994, with the publication of the results of several clinical trials on statin drugs, and the subsequent appearance of national and international guidelines for cholesterol lowering in coronary prevention. There has also been considerable development in the definition of cardiovascular risk, and the methodology for identifying high-risk patients.
All of these aspects are addressed fully in the new edition. In addition, the book offers helpful summaries of the background biochemistry of lipoprotein metabolism and atherosclerosis where relevant, putting the subject in the context of its pathophysiology and epidemiology. The text relating to clinical aspects has a strong evidence base, reviewing, in particular, areas of uncertainty and controversy.
Drawing on the wealth of experience of the author, and representing his widely respected views on the subject, readers will find this comprehensive, well-referenced and accessible book invaluable.
Interactions between the immune and nervous systems are involved in many disease processes. Modulation of inflammation can provide an important opportunity to enhance regeneration within the central nervous system. This authoritative book defines the key cellular players in mounting an inflammatory response and highlights critical factors in the target organ that influence the nature of that response and its capacity either to damage or protect the brain. Several key clinical areas are highlighted – particularly autoimmune diseases of the nervous system including multiple sclerosis, as well as microbiological and traumatic challenges; the book therefore provides both a summary of the basic science background as well as practical, clinical-friendly guidelines to management. The book will be of interest to a wide range of physicians, including neurologists, neurosurgeons, neurorehabilitationists, infectious disease physicians, and clinical neuroscientists, as well as neuroscientists and immunologists.
Traumatic events and disasters are an unexpected but not uncommon aspect of our lives. This book describes the field of disaster mental and behavioral health and is directed at fostering resilience and recovery, whilst recognizing that such events lead to mental illness, distress and health risk behaviors, all of which should be planned for and considered in early interventions. Psychological first aid is discussed, as well as the potential role of psychopharmacology and the relevance of culture in the setting of the disaster. This is essential reading for clinicians who might be involved in a mass trauma situation, along with educators and students in the increasing numbers of educational programs relating to the preparation and response to mass trauma and disaster situations. It should be read by policy makers and public health specialists who must understand the impact of disaster on the person and the systems in which we live.
Mathematical modelling of physiological systems promises to advance our understanding of complex biological phenomena and pathophysiology of diseases. In this book, the authors adopt a mathematical approach to characterize and explain the functioning of the gastrointestinal system. Using the mathematical foundations of thin shell theory, the authors patiently and comprehensively guide the reader through the fundamental theoretical concepts, via step-by-step derivations and mathematical exercises, from basic theory to complex physiological models. Applications to nonlinear problems related to the biomechanics of abdominal viscera and the theoretical limitations are discussed. Special attention is given to questions of complex geometry of organs, effects of boundary conditions on pellet propulsion, as well as to clinical conditions, e.g. functional dyspepsia, intestinal dysrhythmias and the effect of drugs to treat motility disorders. With end of chapter problems, this book is ideal for bioengineers and applied mathematicians.
More than just a Board review for USMLE Steps 2 and 3, “Blueprints Medicine, Fourth Edition” can help you during clerkship rotations and subinternship. This popular “Blueprints” book has been refined and updated while keeping the concise, organized style and clinical high-yield content of previous editions. Features include: USMLE-style questions and answers with full explanations; Key Points in every section; and a color-enhanced design that increases the usefulness of figures and tables. This edition’s art program has been thoroughly updated. Each chapter in this edition ends with evidence-based references (journals) for students to do additional reading/research.
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