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This book describes the development of systems of magnetic resonance imaging using the higher magnetic field strength of 3 tesla, in comparison to the current gold standard of 1.5 tesla. These new systems of MRI make it possible to perform with high spatial, temporal and contrast resolution not only morphological examinations but also functional studies on spectroscopy, diffusion, perfusion, and cortical activation, thus helping research and providing an important tool for routine diagnostic activity. At the same time the new systems offer unparalleled sensitivity and specificity in the numerous conditions of neuroradiological interest.
This textbook takes as a premise that, in order to make intelligent diagnosis and provide a rational treatment in disorders of the nervous system, it is necessary to develop the capacity to answer the basic questions of clinical neurology:
Intercellular communication is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their environment is the basis for growth and development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, diabetes, and neurological and psychiatric disorders. There is substantial drug development concentrating on this and intercellular communication is the basis of much of neuropharmacology. By understanding cell signalling, diseases may be treated effectively and, theoretically, artificial tissues may be yielded. Neurotransmitters/receptors, synaptic structure and organization, gap junctions, neurotrophic factors and neuropeptides are all explored in this volume, as are the ways in which signalling controls neuroendocrinology, neuroimmunology and neuropharmacology. Intercellular Communication in the Nervous System provides a valuable desk reference for all scientists who consider signalling.
“Neurophysiologic intraoperative monitoring (IOM) neurologic monitoring during complex operative procedures is increasingly used to help prevent damage to the nervous system during surgery. Intraoperative Neurophysiology discusses all aspects of IOM with a hands- on approach to this challenging and exciting new frontier. Everything is covered from set-up, monitoring and mapping, troubleshooting, interpretation of results, and medical management. Interweaving contributions from neurologists and surgeons, the book presents a practical integrated blueprint for effective neurophysiological testing in the operating theater.
Intraoperative Neurophysiology is visual and comprehensive in scope and coverage. It begins by reviewing basic neurophysiologic and neuroanatomic knowledge and presents detailed technical information on each basic test, providing the foundation necessary for choosing the right test and customizing monitoring and mapping according to the specifics of individual surgical procedures.
Intraoperative Neurophysiology utilizes a unique structure to provide insights into successful monitoring practices and techniques. The book uses the steps of each surgical procedure as the skeleton upon which the IOM procedure is built, thereby presenting a developmental step-by-step approach to IOM procedures and the possible complications and pitfalls – that may arise at different moments of the surgery. In addition, it promotes and encourages the use of EEG in the operating room, and offers unprecedented coverage of ECoG, functional mapping, and EEG monitoring.
With over 275 illustrations, numerous tables, and the most important clinical points made in writing and exemplified graphically, Intraoperative Neurophysiology: Monitoring and Mapping delivers in words and pictures everything one needs to know to master the art and science of intraoperative neurophysiologic procedure and reduce the operative risk of neurological damage in surgical patients.”
H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a “better understanding of the epilepsies and seek more rational methods of their prevention and treatment.” Since then, basic and clinical researchers in epilepsy have gathered together every decade
and a half with these goals in mind – assessing where epilepsy research has been, what it has accomplished, and where it should go. In 1999, the third volume of BME was named in honor of H.H. Jasper. In line with the enormous expansion in the understanding of basic epilepsy mechanisms over the past
four decades, this fourth edition of Jasper’s BME is the most ambitious yet. In 90 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility, and ultimately epileptogenesis. It provides a framework for expanding the epilepsy genome and understanding the complex heredity responsible for common epilepsies as it explores disease
Traumatic brain injury (TBI) is a public health issue of worldwide proportions, affecting motorists, victims of interpersonal violence, athletes, military service members, and Veterans, among others. Management of Adults with Traumatic Brain Injury provides evidence-informed guidance on the core topics in brain injury medicine, including the epidemiology and pathophysiology of TBI, the medical evaluation and neuropsychological assessment of persons with TBI, and the common cognitive, emotional, behavioral, and other neurological disturbances for which persons with TBI and their families seek clinical care. Impressive breadth and depth of coverage, logical structure, clinically rich detail, and concise presentation make Management of Adults with Traumatic Brain Injury a must-read for every physician, nurse, and mental health practitioner working to improve the lives of persons with TBI.
The thoroughly updated Twelfth Edition of this classic retains the organization, practicality, and readability that makes Merritt’s Neurology one of the most popular texts among neurologists, primary care physicians, and residents reviewing for psychiatry or neurology boards. In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies.
An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular, with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy.
Fully updated throughout, this popular book explains the history, rationale, and detailed descriptions of the class of soft tissue manipulation methods known collectively as NMT techniques.
Molecular sensors for cardiovascular homeostasis donna h wang md faha faan biological homeostasis is maintained via intact function of an array of molecules . P1 ote sph p2 ote svny334 wang february 14 2007 1512 molecular sensors for cardiovascular homeostasis edited by donna h wang department of medicine neuroscience . Molecular sensors for cardiovascular homeostasis dh wang on amazoncom free shipping on qualifying offers the biomolecular basis underlying essential . Biological homeostasis is maintained via intact function of an array of molecules detecting changes of microenvironments inside and outside of the . Get this from a library molecular sensors for cardiovascular homeostasis donna h wang molecular sensors for cardiovascular homeostasis donna h wang md faha
This volume tries to link the new concepts and discoveries in the field of sensorimotor coordination. It contains the main contributions of participants of an international symposium held in Lyon in 2001 entitled “Neural control of space coding and action production”. The book emphasizes the reciprocal relationship between perception and action, and the essential role of active sensorimotor organization or reorganization in building up perceptual and motor representations of the self and of the external world.
As the title suggests, and unlike other existing books on sleep medicine, Neuroendocrine Correlates of Sleep/Wakefulness will be devoted primarily to endocrine regulation of the behavioral state control. It will address a wide spectrum of sleep./wakefulness phenomena (both animals and humans), including pathogenesis, diagnosis, and management.From molecular biology to applied clinical therapy, sleep research has been transformed in the last few years from a research backwater to an important interdisciplinary field.Anyone who regularly reads the literature on sleep, biological rhythms, or neuroendocrinology is aware that one of the subspecialties within sleep medicine, the neuroendocrine correlates of sleep/wakefulness, has in particular experienced a growth rate that is even faster than that of the field as a whole. To a significant extent this has been due to the introduction of new research technologies.
The widespread adoption of a range of new methods in sleep research has opened a window into activities at the cellular and molecular level, which previously had been tightly closed. Consequently these activities are being characterized with a degree of precision and sensitivity that is without precedent. This volume invites the reader to explore the new vistas that have been opened onto the neuroendocrine frontier of sleep medicine. The editors have selectively identified a number of key articles having a citation frequency, which is considerably above the norm or which otherwise have contributed importantly to defining the neuroendocrine perspective.
This new volume on Neuroendocrine Correlates of Sleep/Wakefulness is an up-to-date resource of research summaries and reviews written by major contributors to the fields of sleep, biological rhythms and neuroendocrinology. Its coverage is broad and its basic and clinical science reviews are detailed.
Progress in genetic knowledge is profoundly affecting medical practice, and no clinical specialty has more diseases associated with genetic mutations than neurology. As a more complete picture of the genes which give rise to neurological disease is obtained, trainee and practising neurologists need a guide to basic principles and the more important clinical entities with a genetic component. It is against this background that Neurogenetics: A Guide for Clinicians has been written. The book opens with coverage of genetic testing and counselling. Subsequent chapters discuss genetic factors for all the major neurological diseases, including epilepsy, Alzheimer’s disease, Parkinsonism and muscular dystrophies. No book in this field can hope to be fully up to date with the latest research; rather this work provides a framework on which to add new genetic discoveries. Neurogenetics: A Guide for Clinicians provides a synoptic overview for neurologists, medical geneticists and scientists working in the field.
In the past 20 years, neuroimaging has provided us with a wealth of data regarding human memory. However, to what extent can neuroimaging constrain, support or falsify psychological theories of memory? To what degree is research on the biological bases of memory actually guided by psychological theory?
In looking at the close interaction between neuroimaging research and psychological theories of human memory, this book presents a state-of-the-art exploration of imaging research on human memory, along with accounts of the significance of these findings with regard to fundamental psychological questions. The book starts with a summary of some of the conceptual problems we face in understanding neuroimaging data. It then looks at the four areas of human memory research that have been most intensively studied with modern brain imaging tools – Learning and consolidation, Working memory control processes and storage, Long-term memory representations, and Retrieval control processes. Throughout, the book shows how brain imaging methods, such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), can help us increase our knowledge of how human memory is organized, how memory representations are stored, consolidated and retrieved, and how access to memory contents is controlled. With all chapters written by leading researchers in the field, the book will be essential for all those interested in the psychology and neuroscience of memory.
Although there appears to be a general understanding that the human brain functions similarly in women and in men, an increasing body of knowledge indicates that neuronal connectivity, recruitment, and disease patterns exhibit gender differences. There are clear gender differences in genetic expression, physiologic function, metabolism, hormonal makeup and psychosocial profile, which often modify the clinical expression of neurologic and other diseases. In addition, ethnic, cultural and economic factors are frequently overlooked in dealing with health problems of women, even though they undoubtedly have a strong influence on the clinical course of the illness.
The second edition of Neurologic Disease in Women, the only text to specifically cover this important topic, will help Physicians and other medical personnel seeking information relevant to clinical care. Sections address general anatomic, hormonal, epidemiologic and drug aspects of women’s health; neurologic conditions that arise during childhood, pregnancy, adulthood and old age in females; and particular neurologic conditions that present differently or predominantly in females.
There have been important advances in several areas prompting new chapters, new approaches and additional information provided in chapters on hormonal effects in women and the use of HRT; the adverse effects of antiepileptic drugs on hormonal homeostasis, weight and bone health; and cardiovascular diseases in women. New chapters include ones on reproductive and metabolic disorders with AED use and on movement disorders.
CURRENT Diagnosis & Treatment Neurology, 2e provides busy clinicians with practical, up-to-date strategies for assessing and managing the most frequently seen neurologic conditions in adults and children.
An introductory textbook of neurology in the Illustrated Colour Text series, making full use of all the usual features of the series – double-page spreads, short paragraphs, summary boxes, attractive use of colour etc.
A clear, concise, and approachable writing style helps students understand neurology in the context of speech-language pathology. Supplemented by a wealth of new illustrations and learning features for students, this new edition helps to demystify this often-daunting subject matter. The 5th edition also introduces a new author, Dr Richard Adler, who brings a fresh perspective and an impressive clinical background.
Dr Jagjit Chopra is a very renowned Neurologist. He was awarded Padam Bhushan in 2008 for exceptional qualities in Medicine. He was the Founder President Indian Academy of Neurology and Past President Neurological Society of India. He was the Head Department of Neurology, Postgraduate Institute of Medical Education and Research Chandigarh (1968-1995). He was the Founder Director, Principal, Govt. Medical College Chandigarh; Secretary Medical Education and Research Chandigarh Administration; Consultant Neurologist, Armed Forces of India.
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